Journal of Modern Rehabilitation 2016. 10(1):7-12.

Relationship between Disability Severity and Activity of Daily Living in People with Multiple Sclerosis
Marzeyeh Mousai, Afsoon Hassani-Mehraban, Malahat Akbarfahimi, SeyedMasoud Nabavi


Introduction: Multiple sclerosis (MS) is one of the most common disabling diseases in young adults. Common manifestations include fatigue, bladder and bowel disorders, pain, mobility problems, and cognitive impairment. These symptoms seriously affect the activity of daily living (ADL) of people with MS. The purpose of this study to investigate relationship between disability severity and ADL in people with MS.
Material and Methods: A total of 112 people with MS enrolled in this study. These people were evaluated by Barthel index, Mini Mental Status Examination, the Extended Disability Status Scale for ADL, cognitive ability and severity of disability.
Results: In linear regression analysis, independence in ADL is the best of predictor (69%) of disability severity in people with MS. The Pearson correlation test between the severity of disability and independence in ADL showed a significant relationship.
Conclusion: Independence in performing ADL can predict disability severity in people with MS.


Activity of daily living; Multiple sclerosis; Disability severity

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Svestkova O, Angerova Y, Sladkova P, KeclikovaB, Bickenbach JE, Raggi A. Functioning and disability in multiple sclerosis. Disabil Rehabil 2010; 32(Suppl 1): S59-S67.

Hamidizadeh S, Masoudi R, Ahmadi F, Mohammadi E. Evaluation of the effect of self- care program based on the orem framework on the physical quality of life in multiple sclerosis patients. J Shaheed Sadoughi Univ Med Sci 2010;

(2): 20-9. [In Persian].

Sahraian MA, Pakdaman H, Harandi AA. Is it time to revise the classification of geographical distribution of multiple sclerosis? Iran J Neurol 2012; 11(2): 77-8.

Harirchian MH, Sahraian MA, Hosseinkhani A, Amirzargar N. Level of attitude toward complementary and alternative medicine among Iranian patients with multiple sclerosis. Iran J Neurol 2014; 13(1): 13-8.

Pedretti LW, Pendleton HM, Schultz-Krohn W.Pedretti's Occupational Therapy: Practice Skills for Physical Dysfunction. Philadelphia, PA: Mosby/Elsevier, 2006.

Basak T, Unver V, Demirkaya S. Activities of daily living and self-care agency in patients with multiple sclerosis for the first 10 years. Rehabil Nurs 2015; 40(1): 60-5.

Karhula ME, Kanelisto KJ, Ruutiainen J, Hamalainen PI, Salminen AL. The activities and participation categories of the ICF Core Sets for multiple sclerosis from the patient perspective. Disabil Rehabil 2013; 35(6): 492-7.

Mansson E, Lexell J. Performance of activities of daily living in multiple sclerosis. Disabil Rehabil 2004; 26(10): 576-85.

Holper L, Coenen M, Weise A, Stucki G, Cieza A, Kesselring J. Characterization of functioning in multiple sclerosis using the ICF. J Neurol 2010;257(1): 103-13.

Ghandi DM, Akbarfahimi M, Nabavi SM, Hassani MA, Jafarzadehpur E. Can hand dexterity predict the disability status of patients with multiple sclerosis? Med J Islam Repub Iran 2015; 29: 255.

Feys P, Romberg A, Ruutiainen J, Ketelaer P.Interference of upper limb tremor on daily life activities in people with multiple sclerosis. Occup Ther Health Care 2004; 17(3-4): 81-95.

Cohen RA, Kessler HR, Fischer M. The Extended Disability Status Scale (EDSS) as a predictor of impairments of functional activities of daily living in multiple sclerosis. J Neurol Sci 1993; 115(2):132-5.

Paltamaa J, Sarasoja T, Leskinen E, Wikstrom J, Malkia E. Measures of physical functioning predict self-reported performance in self-care, mobility, and domestic life in ambulatory persons with multiple sclerosis. Arch Phys Med Rehabil 2007; 88(12): 1649-57.

Foroughan M, Jafari Z, Shirin Bayan P, Ghaem Magham Faraahani Z, Rahgozar M. Validation of mini- mental state examination (MMSE) in the elderly population of Tehran. Adv Cogn Sci 2008;10(2): 29-37. [In Persian].

Granger CV, Albrecht GL, Hamilton BB. Outcome of comprehensive medical rehabilitation: measurement by PULSES profile and the Barthel Index. Arch Phys Med Rehabil 1979; 60(4): 145-54.

Hacke W, Kaste M, Fieschi C, von Kummer R, Davalos A, Meier D, et al. Randomised double- blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II). Second European- Australasian Acute Stroke Study Investigators. Lancet 1998; 352(9136): 1245-51.

Oveisgharan S, Shirani S, Ghorbani A, Soltanzade A, Baghaei A, Hosseini S, et al. Barthel index in a Middle-East country: translation, validity and reliability. Cerebrovasc Dis 2006; 22(5-6): 350-4.

Hennessey A, Robertson NP, Swingler R, Compston DA. Urinary, faecal and sexual dysfunction in patients with multiple sclerosis. J Neurol 1999; 246(11): 1027-32.

Glanz BI, Healy BC, Rintell DJ, Jaffin SK, Bakshi R, Weiner HL. The association between cognitive impairment and quality of life in patients with early multiple sclerosis. J Neurol Sci 2010; 290(1-2): 75-9.

Amato MP, Ponziani G, Siracusa G, Sorbi S.Cognitive dysfunction in early-onset multiple sclerosis: a reappraisal after 10 years. Arch Neurol 2001; 58(10): 1602-6.


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