Is Electrical Stimulation Useful for Patients with Duchenne Muscular Dystrophy? A Mini-review
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Abstract
Duchenne muscular dystrophy (DMD) is a hereditary progressive neuromuscular disease of childhood. The survival rate of DMD patients is extremely low. In physiotherapy, electrical stimulation is frequently applied to rehabilitate these patients. The present study aimed to evaluate the effects of electrical stimulation on the muscles of patients with DMD. In this regard limited relevant studies were found, some of which reported the positive effects of low-frequency electrical stimulation on improving muscle strength. Conversely, there were reports of the detrimental effects of electrical stimulation on muscle fibers. Overall, there is no standard guideline for electrical stimulation in patients with DMD, and further research is required with adequate sample size and follow-up.
Verhaart IE, Aartsma-Rus A. Therapeutic developments for duchenne muscular dystrophy. Nature Reviews Neurology. 2019; 15(7):373-86. [DOI:10.1038/s41582-019-0203-3] [PMID]
Ryder S, Leadley R, Armstrong N, Westwood M, De Kock S, Butt T, et al. The burden, epidemiology, costs, and treatment for duchenne muscular dystrophy: An evidence review. Orphanet Journal of Rare Diseases. 2017; 12(1):1-21. [DOI:10.1186/s13023-017-0631-3] [PMID] [PMCID]
Crisafulli S, Sultana J, Fontana A, Salvo F, Messina S, Trifirò G. Global epidemiology of duchenne muscular dystrophy: An updated systematic review and meta-analysis. Orphanet Journal of Rare Diseases. 2020; 15:1-20. [DOI:10.1186/s13023-020-01430-8] [PMID] [PMCID]
Werneck LC, Lorenzoni PJ, Ducci RD, Fustes OH, Kay CS, Scola RH. Duchenne muscular dystrophy: An historical treatment review. Arquivos de Neuro-Psiquiatria. 2019; 77:579-89. [DOI:10.1590/0004-282x20190088] [PMID]
Kolwicz Jr SC, Hall JK, Moussavi-Harami F, Chen X, Hauschka SD, Chamberlain JS, et al. Gene therapy rescues cardiac dysfunction in duchenne muscular dystrophy mice by elevating cardiomyocyte deoxy-adenosine triphosphate. JACC: Basic to Translational Science. 2019; 4(7):778-91. [DOI:10.1016/j.jacbts.2019.06.006] [PMID] [PMCID]
Dehail P, Duclos C, Barat M. Electrical stimulation and muscle strengthening. InAnnales de réadaptation et de médecine physique 2008; 51(6):441-51. [DOI:10.1016/j.annrmp.2008.05.001] [PMID]
Scott OM, Hyde SA, Vrbová G, Dubowitz V. Therapeutic possibilities of chronic low-frequency electrical stimulation in children with duchenne muscular dystrophy. Journal of the Neurological Sciences. 1990; 95(2):171-82. [DOI:10.1016/0022-510X(90)90240-N] [PMID]
Scott OM, Vrbová G, Hyde SA, Dubowitz V. Responses of muscles of patients with duchenne muscular dystrophy to chronic electrical stimulation. Journal of Neurology, Neurosurgery, and Psychiatry. 1986; 49(12):1427-34. [DOI:10.1136/jnnp.49.12.1427] [PMID] [PMCID]
Zupan A. Long-term electrical stimulation of muscles in children with Duchenne and Becker muscular dystrophy. Muscle & Nerve. 1992; 15(3):362-7. [DOI:10.1002/mus.880150316] [PMID]
Zupan A, Gregoric M, Valencic V, Vandot S. Effects of electrical stimulation on muscles of children with Duchenne and Becker muscular dystrophy. Neuropediatrics. 1993; 24(4):189-92. [DOI:10.1055/s-2008-1071537] [PMID]
Milner-Brown HS, Miller RG. Muscle strengthening through electric stimulation combined with low-resistance weights in patients with neuromuscular disorders. Archives of Physical Medicine and Rehabilitation. 1988; 69(1):20-4. [Link]
Yoshida M, Matsuzaki T, Date M, Wada K. Skeletal muscle fiber degeneration in mdx mice induced by electrical stimulation. Muscle & Nerve. 1997; 20(11):1422-32. [DOI:10.1002/(SICI)1097-4598(199711)20:113.0.CO;2-3]
Duchenne G-B. On localized electrization and its application to pathology and therapeutics. Philadelphia: Lindsay & Blakiston; 1871. [Link]
Freund H-J. Motor unit and muscle activity in voluntary motor control. Physiological Reviews. 1983; 63(2):387-436. [DOI:10.1152/physrev.1983.63.2.387] [PMID]
Scott O, Vrbova G, Hyde S, Dubowitz V. Effects of chronic low frequency electrical stimulation on normal human tibialis anterior muscle. Journal of Neurology, Neurosurgery & Psychiatry. 1985; 48(8):774-81. [DOI:10.1136/jnnp.48.8.774] [PMID] [PMCID]
Navarrete R, Vrbová G. Changes of activity patterns in slow and fast muscles during postnatal development. Developmental Brain Research. 1983; 8(1):11-9. [DOI:10.1016/0165-3806(83)90152-9]
Dubowitz V. Responses of diseased muscle to electrical and mechanical intervention. Ciba Foundation Symposium. 1988; 138:240-55. [DOI:10.1002/9780470513675.ch15] [PMID]
VRBOVA G. Neuromuscular diseases viewed as a disturbance of nerve-muscle interactions. Research Monographs in Cell and Tissue Physiology. 1983; 8:359-83. [Link]
Edwards RH, Chapman SJ, Newham DJ, Jones DB. Practical analysis of variability of muscle function measurements in duchenne muscular dystrophy. Muscle & Nerve. 1987; 10(1):6-14. [DOI:10.1002/mus.880100104] [PMID]
Gregoric MV, Valencic V, Zupan A, Klemen A. Effects of electrical stimulation on muscles of patients with progressive muscular disease. In: Wallinga W, Boudewijn H, Boom K, de Vries J, editors. Electrophysiological kinesiology. Electrophysiological Kinesiology: Proceedings of the 7th congress of the international society of electrophysiological kinesiology, held in Enschede, the Netherlands, 20-23 June 1988. Amsterdam: Excerpta Medica; 1988. [Link]
Lenman JA. Integration and analysis of the electromyogram and related techniques. In: Walton, JN, editor. Disorders of voluntary muscle. New York: Churchill Livingstone; 1981. [Link]
Ryder S, Leadley R, Armstrong N, Westwood M, De Kock S, Butt T, et al. The burden, epidemiology, costs, and treatment for duchenne muscular dystrophy: An evidence review. Orphanet Journal of Rare Diseases. 2017; 12(1):1-21. [DOI:10.1186/s13023-017-0631-3] [PMID] [PMCID]
Crisafulli S, Sultana J, Fontana A, Salvo F, Messina S, Trifirò G. Global epidemiology of duchenne muscular dystrophy: An updated systematic review and meta-analysis. Orphanet Journal of Rare Diseases. 2020; 15:1-20. [DOI:10.1186/s13023-020-01430-8] [PMID] [PMCID]
Werneck LC, Lorenzoni PJ, Ducci RD, Fustes OH, Kay CS, Scola RH. Duchenne muscular dystrophy: An historical treatment review. Arquivos de Neuro-Psiquiatria. 2019; 77:579-89. [DOI:10.1590/0004-282x20190088] [PMID]
Kolwicz Jr SC, Hall JK, Moussavi-Harami F, Chen X, Hauschka SD, Chamberlain JS, et al. Gene therapy rescues cardiac dysfunction in duchenne muscular dystrophy mice by elevating cardiomyocyte deoxy-adenosine triphosphate. JACC: Basic to Translational Science. 2019; 4(7):778-91. [DOI:10.1016/j.jacbts.2019.06.006] [PMID] [PMCID]
Dehail P, Duclos C, Barat M. Electrical stimulation and muscle strengthening. InAnnales de réadaptation et de médecine physique 2008; 51(6):441-51. [DOI:10.1016/j.annrmp.2008.05.001] [PMID]
Scott OM, Hyde SA, Vrbová G, Dubowitz V. Therapeutic possibilities of chronic low-frequency electrical stimulation in children with duchenne muscular dystrophy. Journal of the Neurological Sciences. 1990; 95(2):171-82. [DOI:10.1016/0022-510X(90)90240-N] [PMID]
Scott OM, Vrbová G, Hyde SA, Dubowitz V. Responses of muscles of patients with duchenne muscular dystrophy to chronic electrical stimulation. Journal of Neurology, Neurosurgery, and Psychiatry. 1986; 49(12):1427-34. [DOI:10.1136/jnnp.49.12.1427] [PMID] [PMCID]
Zupan A. Long-term electrical stimulation of muscles in children with Duchenne and Becker muscular dystrophy. Muscle & Nerve. 1992; 15(3):362-7. [DOI:10.1002/mus.880150316] [PMID]
Zupan A, Gregoric M, Valencic V, Vandot S. Effects of electrical stimulation on muscles of children with Duchenne and Becker muscular dystrophy. Neuropediatrics. 1993; 24(4):189-92. [DOI:10.1055/s-2008-1071537] [PMID]
Milner-Brown HS, Miller RG. Muscle strengthening through electric stimulation combined with low-resistance weights in patients with neuromuscular disorders. Archives of Physical Medicine and Rehabilitation. 1988; 69(1):20-4. [Link]
Yoshida M, Matsuzaki T, Date M, Wada K. Skeletal muscle fiber degeneration in mdx mice induced by electrical stimulation. Muscle & Nerve. 1997; 20(11):1422-32. [DOI:10.1002/(SICI)1097-4598(199711)20:113.0.CO;2-3]
Duchenne G-B. On localized electrization and its application to pathology and therapeutics. Philadelphia: Lindsay & Blakiston; 1871. [Link]
Freund H-J. Motor unit and muscle activity in voluntary motor control. Physiological Reviews. 1983; 63(2):387-436. [DOI:10.1152/physrev.1983.63.2.387] [PMID]
Scott O, Vrbova G, Hyde S, Dubowitz V. Effects of chronic low frequency electrical stimulation on normal human tibialis anterior muscle. Journal of Neurology, Neurosurgery & Psychiatry. 1985; 48(8):774-81. [DOI:10.1136/jnnp.48.8.774] [PMID] [PMCID]
Navarrete R, Vrbová G. Changes of activity patterns in slow and fast muscles during postnatal development. Developmental Brain Research. 1983; 8(1):11-9. [DOI:10.1016/0165-3806(83)90152-9]
Dubowitz V. Responses of diseased muscle to electrical and mechanical intervention. Ciba Foundation Symposium. 1988; 138:240-55. [DOI:10.1002/9780470513675.ch15] [PMID]
VRBOVA G. Neuromuscular diseases viewed as a disturbance of nerve-muscle interactions. Research Monographs in Cell and Tissue Physiology. 1983; 8:359-83. [Link]
Edwards RH, Chapman SJ, Newham DJ, Jones DB. Practical analysis of variability of muscle function measurements in duchenne muscular dystrophy. Muscle & Nerve. 1987; 10(1):6-14. [DOI:10.1002/mus.880100104] [PMID]
Gregoric MV, Valencic V, Zupan A, Klemen A. Effects of electrical stimulation on muscles of patients with progressive muscular disease. In: Wallinga W, Boudewijn H, Boom K, de Vries J, editors. Electrophysiological kinesiology. Electrophysiological Kinesiology: Proceedings of the 7th congress of the international society of electrophysiological kinesiology, held in Enschede, the Netherlands, 20-23 June 1988. Amsterdam: Excerpta Medica; 1988. [Link]
Lenman JA. Integration and analysis of the electromyogram and related techniques. In: Walton, JN, editor. Disorders of voluntary muscle. New York: Churchill Livingstone; 1981. [Link]
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| Issue | Vol 17 No 2 (2023) | |
| Section | Review Article(s) | |
| DOI | https://doi.org/10.18502/jmr.v17i2.12409 | |
| Keywords | ||
| Duchenne muscular dystrophy Electrical stimulation | ||
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How to Cite
1.
Radinmehr H, Rahbar S. Is Electrical Stimulation Useful for Patients with Duchenne Muscular Dystrophy? A Mini-review. jmr. 2023;17(2):125-128.
