Investigation of Semantic System Defects in Adult Aphasic Patients Following Stroke
Abstract
Introduction: Semantic system plays a key role in all areas of language including understanding and expression of language. Based on a traditional view, the left hemisphere is dominant for processing of various linguistic information, including semantic information. It is believed that lesions in the left hemisphere impair the semantic component of language. In this study, we aim to study different types of semantic impairment in patients with aphasia; so that with early diagnosis of these sematic impairment we can identify patients who need treatment.
Materials and Methods: This is a cross-sectional, descriptive-analytic study. A total of 39 subjects, comprising 13 patients with left cerebral ischemic stroke in the temporoparietal region and 26 healthy subjects, were evaluated using pyramids and palm trees test, concrete and abstract word synonym test, and Bilingual Aphasia Test (BAT).
Results: In concrete and abstract word synonym test, patients with left hemisphere damage had lower performance than the normal group. Only in the verbal version of the pyramids and palm trees test, patients with left hemisphere damage obtained significantly lower scores than the normal participants. In the BAT test, patients with left hemisphere had a heterogeneous performance.
Conclusion: Based on these findings, although a large part of semantic processing is performed by the dominant hemisphere of the brain, the right hemisphere has a complementary role in semantic processing.
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Goodglass H, Kaplan E, Barresi B. The assessment of aphasia and related disorders. Philadelphia: Lippincott Williams & Wilkins; 2001.
Adams RD, Vander Eecken HM. Vascular diseases of the brain. Annual Review of Medicine. 1953; 4(1):213-52. [DOI:10.1146/annurev.me.04.020153.001241] [PMID]
Adler R, MacRitchie K, Engel GL. Psychologic processes and ischemic stroke (Occlusive cerebrovascular disease): I. Observations on 32 Men with 35 strokes. Psychosomatic Medicine. 1971; 33(1):1-30. [DOI:10.1097/00006842-197101000-00001] [PMID]
Gresham GE, Stason WB, Duncan PW. Post-stroke rehabilitation. Pennsylvania: Diane Publishing; 1997.
Spreen O, Risser AH. Assessment of aphasia. Oxford: Oxford University Press; 2003. [PMID]
Caplan D, Hildebrandt N, Makris N. Location of lesions in stroke patients with deficits in syntactic processing in sentence comprehension. Brain. 1996; 119(3):933-49. [DOI:10.1093/brain/119.3.933] [PMID]
Kirshner HS. Handbook of neurological speech and language disorders. Milton Park, Didcot: Taylor & Francis; 1994.
Nelson K. Explorations in the development of a functional semantic system. Child Psychology; 1979.
Duchan R, Linda J, Garcia AK, Lyon JG, Simmons Mackie N. Life participation approach to aphasia: A statement of values for the future. In: Chepy R, editor. Language Intervention Strategies in Aphasia and Related Neurogenic Communication Disorders. South Holland: Wolters Kluwer; 2001
Pourshahid G. Clinician Perspectives on AAC: Current Barriers and New Opportunities [PhD Dissertation]. Toronto: University of Toronto; 2011.
Marslen-Wilson W, Tyler LK. The temporal structure of spoken language understanding. Cognition. 1980; 8(1):1-71. [DOI:10.1016/0010-0277(80)90015-3]
Nilipour R, Pourshahbaz A, Ghoreyshi ZS. Reliability and validity of bedside version of Persian WAB (P-WAB-1). Basic and Clinical Neuroscience. 2014; 5(4):253-8. [PMID] [PMCID]
Radaei M, Mehri A, DastjerdiKazemi M, Jalaei S. [Determination of validity and reliability of Persian picture version (Persian)]. Journal of Modern Rehabilitation. 2013; 7(3):18-23.
Callahan BL, Macoir J, Hudon C, Bier N, Chouinard N, Cossette Harvey M, et al. Normative data for the pyramids and palm trees test in the Quebec-French population. Archives of Clinical Neuropsychology. 2010; 25(3):212-7. [DOI:10.1093/arclin/acq013] [PMID]
Gamboz N, Coluccia E, Iavarone A, Brandimonte MA. Normative data for the Pyramids and Palm Trees Test in the elderly Italian population. Neurological Sciences. 2009; 30(6):453. [DOI:10.1007/s10072-009-0130-y] [PMID]
Howard D, Patterson KE. The Pyramids and Palm Trees Test: A test of semantic access from words and pictures. Bury St Edmunds: Thames Valley Test Company; 1992.
Rami L, Serradell M, Bosch B, Caprile C, Sekler A, Villar A, et al. Normative data for the Boston Naming Test and the Pyramids and Palm Trees Test in the elderly Spanish population. Journal of Clinical and Experimental Neuropsychology. 2008; 30(1):1-6. [DOI:10.1080/13803390701743954] [PMID]
Seyyedin S, Mehri A, DastjerdiKazemi M, Jalaei S. Development of a valid and reliable Concrete and Abstract Word Comprehension Synonym Test in Persian aphasic patients. Journal of Modern Rehabilitation. 2016; 9(5):49-58.
Warrington Pat McKenna Lisa Orpwood EK. Single word comprehension: A concrete and abstract word synonym test. Neuropsychological Rehabilitation. 1998; 8(2):143-54. [DOI:10.1080/713755564]
Nilipour R, Pour Shahbaz A, Ghoreishi ZS, Yousefi A. [Reliability and validity of Persian Aphasia Battery Test (Persian)]. Iranian Journal of Ageing. 2016; 10(4):182-91.
Paradis M, Libben G. The assessment of bilingual aphasia. New York: Psychology Press; 2014. [DOI:10.4324/9781315802138]
Khatoonabadi AR, Hovsepian A, Harley T, Kahlaoui K, Marsolais Y, Joanette Y. The impact of left-and right-hemisphere lesions on the processing of concrete and abstract words in Farsi. Brain and Cognition. 2008; 67(1):25-6.
Friederici AD, Opitz B, Von Cramon DY. Segregating semantic and syntactic aspects of processing in the human brain: An fMRI investigation of different word types. Cerebral Cortex. 2000; 10(7):698-705. [DOI:10.1093/cercor/10.7.698] [PMID]
Fiebach CJ, Friederici AD. Processing concrete words: fMRI evidence against a specific right-hemisphere involvement. Neuropsychologia. 2004; 42(1):62-70. [DOI:10.1016/S0028-3932(03)00145-3]
Binder JR, Desai RH, Graves WW, Conant LL. Where is the semantic system? A critical review and meta-analysis of 120 functional neuroimaging studies. Cerebral Cortex. 2009; 19(12):2767-96. [DOI:10.1093/cercor/bhp055] [PMID] [PMCID]
Anastasia M, Raymer Y, Leslie Y, Gonzalez R. Impairment of word comprehension and production. In: Chapey R, editor. Language Intervention Strategies in Aphasia and Related Neurogenic Communication Disorder. Philiadelphia: Lippincott Williams & Wilkins; 2008.
Jodzio K, Biechowska D, Leszniewska Jodzio B. Selectivity of lexical-semantic disorders in Polish-speaking patients with aphasia: Evidence from single-word comprehension. Archives of Clinical Neuropsychology. 2008; 23(5):543-51. [DOI:10.1016/j.acn.2008.05.005] [PMID]
Jefferies E, Hoffman P, Jones R, Lambon Ralpha MA. The impact of semantic impairment on verbal short-term memory in stroke aphasia and semantic dementia: A comparative study. Journal of Memory and Language. 2008; 58(1):66-87. [DOI:10.1016/j.jml.2007.06.004] [PMID] [PMCID]
Jefferies E, Patterson K, Jones RW, Lambon Ralpha MA, Matthew A. Comprehension of concrete and abstract words in semantic dementia. Neuropsychology. 2009; 23(4):492-9. [DOI:10.1037/a0015452] [PMID] [PMCID]
Soni M, Lambon Ralpha MA, Noonan K, Ehsan S, Hodgson C, Woollams AM. “L” is for tiger: Effects of phonological (mis) cueing on picture naming in semantic aphasia. Journal of Neurolinguistics. 2009; 22(6):538-47. [DOI:10.1016/j.jneuroling.2009.06.002]
Arnal LH, Morillon B, Kell CA, Giraud AL. Dual neural routing of visual facilitation in speech processing. Journal of Neuroscience. 2009; 29(43):13445-53. [DOI:10.1523/JNEUROSCI.3194-09.2009] [PMID]
Duncan J. EPS Mid-Career Award 2004: Brain mechanisms of attention. Quarterly Journal of Experimental Psychology. 2006; 59(1):2-27. [DOI:10.1080/17470210500260674] [PMID]
Duncan J. The Multiple-Demand (MD) system of the primate brain: Mental programs for intelligent behaviour. Trends in Cognitive Sciences. 2010; 14(4):172-9. [DOI:10.1016/j.tics.2010.01.004] [PMID]
Duncan J, Owen AM. Common regions of the human frontal lobe recruited by diverse cognitive demands. Trends in Neurosciences. 2000; 23(10):475-83. [DOI:10.1016/S0166-2236(00)01633-7]
Jefferies E, Lambon Ralph MA. Semantic impairment in stroke aphasia versus semantic dementia: A case-series comparison. Brain. 2006; 129(8):2132-47. [DOI:10.1093/brain/awl153] [PMID]
Chechlacz M, Mantini D, Gillebert CR, Humphreys GW. Asymmetrical white matter networks for attending to global versus local features. Cortex. 2015; 72:54-64. [DOI:10.1016/j.cortex.2015.01.022] [PMID] [PMCID]
Robinson GA, Cipolotti L, Walker DG, Biggs V, Bozzali M, Shallice T. Verbal suppression and strategy use: A role for the right lateral prefrontal cortex. Brain. 2015; 138(4):1084-96. [DOI:10.1093/brain/awv003] [PMID]
Goodglass H, Kaplan E, Barresi B. The assessment of aphasia and related disorders. Philadelphia: Lippincott Williams & Wilkins; 2001.
Adams RD, Vander Eecken HM. Vascular diseases of the brain. Annual Review of Medicine. 1953; 4(1):213-52. [DOI:10.1146/annurev.me.04.020153.001241] [PMID]
Adler R, MacRitchie K, Engel GL. Psychologic processes and ischemic stroke (Occlusive cerebrovascular disease): I. Observations on 32 Men with 35 strokes. Psychosomatic Medicine. 1971; 33(1):1-30. [DOI:10.1097/00006842-197101000-00001] [PMID]
Gresham GE, Stason WB, Duncan PW. Post-stroke rehabilitation. Pennsylvania: Diane Publishing; 1997.
Spreen O, Risser AH. Assessment of aphasia. Oxford: Oxford University Press; 2003. [PMID]
Caplan D, Hildebrandt N, Makris N. Location of lesions in stroke patients with deficits in syntactic processing in sentence comprehension. Brain. 1996; 119(3):933-49. [DOI:10.1093/brain/119.3.933] [PMID]
Kirshner HS. Handbook of neurological speech and language disorders. Milton Park, Didcot: Taylor & Francis; 1994.
Nelson K. Explorations in the development of a functional semantic system. Child Psychology; 1979.
Duchan R, Linda J, Garcia AK, Lyon JG, Simmons Mackie N. Life participation approach to aphasia: A statement of values for the future. In: Chepy R, editor. Language Intervention Strategies in Aphasia and Related Neurogenic Communication Disorders. South Holland: Wolters Kluwer; 2001
Pourshahid G. Clinician Perspectives on AAC: Current Barriers and New Opportunities [PhD Dissertation]. Toronto: University of Toronto; 2011.
Marslen-Wilson W, Tyler LK. The temporal structure of spoken language understanding. Cognition. 1980; 8(1):1-71. [DOI:10.1016/0010-0277(80)90015-3]
Nilipour R, Pourshahbaz A, Ghoreyshi ZS. Reliability and validity of bedside version of Persian WAB (P-WAB-1). Basic and Clinical Neuroscience. 2014; 5(4):253-8. [PMID] [PMCID]
Radaei M, Mehri A, DastjerdiKazemi M, Jalaei S. [Determination of validity and reliability of Persian picture version (Persian)]. Journal of Modern Rehabilitation. 2013; 7(3):18-23.
Callahan BL, Macoir J, Hudon C, Bier N, Chouinard N, Cossette Harvey M, et al. Normative data for the pyramids and palm trees test in the Quebec-French population. Archives of Clinical Neuropsychology. 2010; 25(3):212-7. [DOI:10.1093/arclin/acq013] [PMID]
Gamboz N, Coluccia E, Iavarone A, Brandimonte MA. Normative data for the Pyramids and Palm Trees Test in the elderly Italian population. Neurological Sciences. 2009; 30(6):453. [DOI:10.1007/s10072-009-0130-y] [PMID]
Howard D, Patterson KE. The Pyramids and Palm Trees Test: A test of semantic access from words and pictures. Bury St Edmunds: Thames Valley Test Company; 1992.
Rami L, Serradell M, Bosch B, Caprile C, Sekler A, Villar A, et al. Normative data for the Boston Naming Test and the Pyramids and Palm Trees Test in the elderly Spanish population. Journal of Clinical and Experimental Neuropsychology. 2008; 30(1):1-6. [DOI:10.1080/13803390701743954] [PMID]
Seyyedin S, Mehri A, DastjerdiKazemi M, Jalaei S. Development of a valid and reliable Concrete and Abstract Word Comprehension Synonym Test in Persian aphasic patients. Journal of Modern Rehabilitation. 2016; 9(5):49-58.
Warrington Pat McKenna Lisa Orpwood EK. Single word comprehension: A concrete and abstract word synonym test. Neuropsychological Rehabilitation. 1998; 8(2):143-54. [DOI:10.1080/713755564]
Nilipour R, Pour Shahbaz A, Ghoreishi ZS, Yousefi A. [Reliability and validity of Persian Aphasia Battery Test (Persian)]. Iranian Journal of Ageing. 2016; 10(4):182-91.
Paradis M, Libben G. The assessment of bilingual aphasia. New York: Psychology Press; 2014. [DOI:10.4324/9781315802138]
Khatoonabadi AR, Hovsepian A, Harley T, Kahlaoui K, Marsolais Y, Joanette Y. The impact of left-and right-hemisphere lesions on the processing of concrete and abstract words in Farsi. Brain and Cognition. 2008; 67(1):25-6.
Friederici AD, Opitz B, Von Cramon DY. Segregating semantic and syntactic aspects of processing in the human brain: An fMRI investigation of different word types. Cerebral Cortex. 2000; 10(7):698-705. [DOI:10.1093/cercor/10.7.698] [PMID]
Fiebach CJ, Friederici AD. Processing concrete words: fMRI evidence against a specific right-hemisphere involvement. Neuropsychologia. 2004; 42(1):62-70. [DOI:10.1016/S0028-3932(03)00145-3]
Binder JR, Desai RH, Graves WW, Conant LL. Where is the semantic system? A critical review and meta-analysis of 120 functional neuroimaging studies. Cerebral Cortex. 2009; 19(12):2767-96. [DOI:10.1093/cercor/bhp055] [PMID] [PMCID]
Anastasia M, Raymer Y, Leslie Y, Gonzalez R. Impairment of word comprehension and production. In: Chapey R, editor. Language Intervention Strategies in Aphasia and Related Neurogenic Communication Disorder. Philiadelphia: Lippincott Williams & Wilkins; 2008.
Jodzio K, Biechowska D, Leszniewska Jodzio B. Selectivity of lexical-semantic disorders in Polish-speaking patients with aphasia: Evidence from single-word comprehension. Archives of Clinical Neuropsychology. 2008; 23(5):543-51. [DOI:10.1016/j.acn.2008.05.005] [PMID]
Jefferies E, Hoffman P, Jones R, Lambon Ralpha MA. The impact of semantic impairment on verbal short-term memory in stroke aphasia and semantic dementia: A comparative study. Journal of Memory and Language. 2008; 58(1):66-87. [DOI:10.1016/j.jml.2007.06.004] [PMID] [PMCID]
Jefferies E, Patterson K, Jones RW, Lambon Ralpha MA, Matthew A. Comprehension of concrete and abstract words in semantic dementia. Neuropsychology. 2009; 23(4):492-9. [DOI:10.1037/a0015452] [PMID] [PMCID]
Soni M, Lambon Ralpha MA, Noonan K, Ehsan S, Hodgson C, Woollams AM. “L” is for tiger: Effects of phonological (mis) cueing on picture naming in semantic aphasia. Journal of Neurolinguistics. 2009; 22(6):538-47. [DOI:10.1016/j.jneuroling.2009.06.002]
Arnal LH, Morillon B, Kell CA, Giraud AL. Dual neural routing of visual facilitation in speech processing. Journal of Neuroscience. 2009; 29(43):13445-53. [DOI:10.1523/JNEUROSCI.3194-09.2009] [PMID]
Duncan J. EPS Mid-Career Award 2004: Brain mechanisms of attention. Quarterly Journal of Experimental Psychology. 2006; 59(1):2-27. [DOI:10.1080/17470210500260674] [PMID]
Duncan J. The Multiple-Demand (MD) system of the primate brain: Mental programs for intelligent behaviour. Trends in Cognitive Sciences. 2010; 14(4):172-9. [DOI:10.1016/j.tics.2010.01.004] [PMID]
Duncan J, Owen AM. Common regions of the human frontal lobe recruited by diverse cognitive demands. Trends in Neurosciences. 2000; 23(10):475-83. [DOI:10.1016/S0166-2236(00)01633-7]
Jefferies E, Lambon Ralph MA. Semantic impairment in stroke aphasia versus semantic dementia: A case-series comparison. Brain. 2006; 129(8):2132-47. [DOI:10.1093/brain/awl153] [PMID]
Chechlacz M, Mantini D, Gillebert CR, Humphreys GW. Asymmetrical white matter networks for attending to global versus local features. Cortex. 2015; 72:54-64. [DOI:10.1016/j.cortex.2015.01.022] [PMID] [PMCID]
Robinson GA, Cipolotti L, Walker DG, Biggs V, Bozzali M, Shallice T. Verbal suppression and strategy use: A role for the right lateral prefrontal cortex. Brain. 2015; 138(4):1084-96. [DOI:10.1093/brain/awv003] [PMID]
| Files | ||
| Issue | Vol 12 No 1 (2018) | |
| Section | Research Article(s) | |
| Keywords | ||
| Semantics, Stroke, Brain ischemia, Aphasia | ||
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How to Cite
1.
Borjian Boroujeni N, Yadegar F, Alizadeh Zarei M. Investigation of Semantic System Defects in Adult Aphasic Patients Following Stroke. jmr. 2018;12(1):61-70.
