Tehran University of Medical Sciences Journal of Modern Rehabilitation 2538-385X 0 - 2026 02 02 1451 1451 Maryam Alizadeh Department of Speech Therapy, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran Azar Mehri Department of Speech Therapy, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran Shohreh Jalaie Department of Physiotherapy, School of Rehabilitation, Tehran University of Medical Sciences, Tehran, Iran Edythe A. Strand Mayo College of Medicine, Rochester, Minnesota. United States of America AND Mayo Clinic, Rochester, Minnessota, United States of America 2025 10 20 2026 01 31 Background: To introduce Dynamic Temporal and Tactile Cueing (DTTC), which is one of the treatment methods for Childhood Apraxia of Speech (CAS), and it seems the characteristics make it a suitable option for the treatment of AOS patients. Additionally, no documented treatment protocol has been published in Iran for the treatment of AOS patients so far, so this study protocol intends to investigate the DTTC efficacy in the treatment of Persian-speaking patients with acquired AOS who will be allocated to this study using a non-probability and convenience method. Material and Methods: A single subject study with multiple baseline design across participants was designed to obtain detailed information about intervention procedure on at least three participants' performance and a perceptual scoring system was introduced to measure the accuracy of treated and untreated words and phrases as a dependent variable. Conclusions: This study describes the first research for investigating efficacy of DTTC on AOS patients' speech and the first treatment protocol in the field of treating Persian-speaking patients with AOS. https://jmr.tums.ac.ir/index.php/jmr/article/view/1451