Tehran University of Medical Sciences Journal of Modern Rehabilitation 2538-385X 0 - 2025 12 06 Integrative Physical Therapy Versus Pelvic Floor Muscle Training for Post-Prostatectomy Stress Urinary Incontinence: A Randomized Controlled Trial 1443 1443 Mohammad Sheibanifar Department of Physiotherapy, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran Zahra Ebrahimabadi Department of Physiotherapy, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran Hoda Niknam Department of Physiotherapy, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran Farshad Okhovatian Department of Physiotherapy, School of Rehabilitation, Shahid Beheshti University of Medical Sciences, Tehran, Iran Alireza Akbarzadeh Baghban Proteomics Research Center, Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran Marzieh Mortezanejad Department of Physiotherapy, School of Rehabilitation Sciences, Semnan University of Medical Sciences, Semnan, Iran 2025 10 07 2025 12 06 Background: Post-prostatectomy stress urinary incontinence (PPSUI) is a common complication following radical prostatectomy. This study compared the efficacy of integrative physical therapy (IPT) and supervised pelvic floor muscle training (PFMT) in managing PPSUI. Methods: Sixty-six men aged 50–80 years with PPSUI were randomly assigned to IPT, PFMT, or control groups. The IPT program included electrotherapy, manual therapy, diaphragmatic breathing, and PFMT. The PFMT group received supervised PFMT. The control group received sham electrotherapy. All interventions were delivered in 12 sessions over four weeks. Outcome measures included voided volume, fluid intake, micturition frequency, incontinence frequency, and health-related quality of life assessed using the SF-12 questionnaire. Results: Both IPT and PFMT significantly reduced micturition and incontinence frequency and improved SF-12 scores compared with the control group (p<0.001). The control group showed no significant improvements across any outcome measures. IPT demonstrated superior improvements relative to PFMT in micturition frequency, incontinence frequency, and SF-12 scores (p<0.05). Conclusion: Both IPT and PFMT are effective for PPSUI, with IPT showing greater overall efficacy. https://jmr.tums.ac.ir/index.php/jmr/article/view/1443